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nesvacumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-ANGPT2 Therapeutic Antibody TAB-769 1mg Please Inquiry
Product Detail
Cat
TAB-769
Product Overview
Recombinant human monoclonal antibody expressed in CHO binding to human ANGPT2. Nesvacumab is a monoclonal antibody designed for the treatment of cancer.
Target
ANGPT2
Type
IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
CAS
1296818-77-3
Predicted N terminal
EVQLVESG
Molecular Weight
144.9 kDa
Purity
>95.0% as determined by analysis by RP-HPLC.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Introduction
Nesvacumab is a monoclonal antibody designed for the treatment of cancer.
Antigen Description
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
Function
metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding;
Gene ID
285
Synonyms
ANGPT2; angiopoietin 2; angiopoietin-2; Ang2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a; ANG2; AGPT2;
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