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Raxibacumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-B. anthracis anthrax protective antigen (PA) Therapeutic Antibody (ABthrax) TAB-224 1mg Please Inquiry
Product Detail
Cat
TAB-224
Product Overview
Recombinant monoclonal antibody to Bacillus anthracis protective antigen. Raxibacumab is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax. Its efficacy has been proven in rabbits and monkeys.
Target
Bacillus anthracis
Type
IgG1 - lambda
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
B. anthracis
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
CAS
565451-13-0
Trade name
abthrax
Specificity
Tested positive against native B. anthracis antigen.
Molecular Weight
142930
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Introduction
This is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax.
Antigen Description
Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments.
Keywords
anthrax PA; Anthrax Protective Antigen; Anthrax toxins translocating protein; Bacillus anthracis Protective Antigen; PA 83; PA; PA83; Pag; PagA; Protective antigen
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