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bezlotoxumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-C. diff toxin B Therapeutic Antibody TAB-725 1mg Please Inquiry
Product Detail
Cat
TAB-725
Product Overview
Recombinant human monoclonal antibody expressed in CHO binding to toxin B [C. difficile]. Bezlotoxumab is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infection.
Target
toxin B [C. difficile]
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
C. difficile
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, WB and most other immunological methods.
CAS
1245634-25-6
Predicted N terminal
EVQLVQSG
Molecular Weight
145.6 kDa
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Introduction
Clostridium difficile Toxin B (tcdB or ToxB) is a glucosyltranferase which is known to innactivate Rho, Cdc42 and Rac within target cells. This toxin is encoded on a pathogenicity region of the C. difficile chromossome and is expressed during the log and stationary phases of growth in response to a variety of environmental stimuli.
Antigen Description
Clostridium difficile Toxin B (tcdB or ToxB) is a glucosyltranferase which is known to innactivate Rho, Cdc42 and Rac within target cells. This toxin is encoded on a pathogenicity region of the C. difficile chromossome and is expressed during the log and stationary phases of growth in response to a variety of environmental stimuli.
Keywords
C. difficile Toxin B; Clostridium difficile Toxin B; Cytotoxin B; tcdB; toxB; Toxin B
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