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ontuxizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-CD248 Therapeutic Antibody TAB-773 1mg Please Inquiry
Product Detail
Cat
TAB-773
Product Overview
Recombinant chimeric/humanized hybrid (mouse/human) antibody expressed in CHO binding to human CD248. Ontuxizumab is a monoclonal antibody designed for the treatment of cancer.
Target
CD248
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS
946415-62-9
Predicted N terminal
QVQLQESG
Molecular Weight
147.0 kDa
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Introduction
Ontuxizumab is a monoclonal antibody designed for the treatment of cancer and binds to TEM1.
Antigen Description
Endosialin is a protein that in humans is encoded by the CD248 gene.Endosialin is a member of the "Group XIV", a novel family of C-type lectin transmembrane receptors which play a role not only in cell-cell adhesion processes but also in host defence. This family comprise two other members, CD93 and Thrombomodulin which are better characterized. Even though the function of endosialin remains elusive, its expression has been associated with angiogenesis in the embryo, uterus and in tumor development and growth.
Function
binding; calcium ion binding; molecular_function; sugar binding;
Gene ID
57124
Synonyms
CD248; CD248 molecule, endosialin; CD164 sialomucin like 1 , CD164L1, CD248 antigen, endosialin; endosialin; TEM1; tumor endothelial marker 1; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; CD164L1; MGC119478; MGC119479;
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