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lintuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-CD33 Therapeutic Antibody (ZAMYL/Smart) TAB-756 1mg Please Inquiry
Product Detail
Cat
TAB-756
Product Overview
Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD33. Lintuzumab is a humanized monoclonal antibody used in the treatment of cancer.
Target
CD33
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
Sp2/0 mouse myeloma cells
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
CAS
166089-32-3
Trade name
zamyl/smart
Predicted N terminal
QVQLVQSG
Molecular Weight
46.96 kDa
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Introduction
Lintuzumab (SGN-33) is a humanized monoclonal antibody used in the treatment of cancer.
Antigen Description
CD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage.It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.It binds sialic acids, therefore is a member of the SIGLEC family of lectins.
Function
receptor activity; sugar binding;
Gene ID
945
Synonyms
CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3;
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