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eldelumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-CXCL10 Therapeutic Antibody TAB-742 1mg Please Inquiry
Product Detail
Cat
TAB-742
Product Overview
Recombinant human monoclonal antibody expressed in CHO binding to human CXCL10. Eldelumab is a monoclonal antibody designed for the treatment of Crohn's disease and ulcerative colitis.
Target
C-X-C motif chemokine 10
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
CAS
946414-98-8
Predicted N terminal
QMQLVESG
Molecular Weight
146.5 kDa
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Introduction
Eldelumab is a monoclonal antibody designed for the treatment of Crohn's disease and ulcerative colitis.
Antigen Description
This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.
Function
cAMP-dependent protein kinase regulator activity; chemokine activity; receptor binding;
Gene ID
3627
Synonyms
CXCL10; chemokine (C-X-C motif) ligand 10; INP10, SCYB10, small inducible cytokine subfamily B (Cys X Cys), member 10; C-X-C motif chemokine 10; C7; crg 2; gIP 10; IFI10; IP 10; mob 1; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10;
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