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setoxaximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-E. coli Stx2A Therapeutic Antibody TAB-H61 1mg Please Inquiry
Product Detail
Cat
TAB-H61
Product Overview
Recombinant Mouse antibody to E. coli Stx2
Type
IgG1 - kappa
Species Reactivity
E. coli
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
CAS
1351470-17-1
Specificity
shiga toxin type 2 (shiga toxin-producing Escherichia coli (STEC), stx2, Stx2, Stx-2, Shiga-like toxin 2, SLT-2, SLT-II) A subunit [Escherichia coli]
Protein Construction
gamma1 heavy chain (1-451) [Mus musculus VH (IGHV1-39*01 – (IGHD) – IGHJ1*01) [8.8.12] (1-119)– linker (120-121) – Homo sapiens IGHG1*01 (CH1 (122-219), hinge (220-234), CH2 (235-344), CH3(345-449), CHS (450-451) (122-451)], (224-220') – disulfide withkappa light chain (1'-220') [Mus musculus V-KAPPA (IGKV8-30*01 – IGKJ5*01) [12.3.9] (1'-113') –Homo sapiens IGKC*01 (114'-220')]; dimer (230-230'':233-233'') – bisdisulfide
Purity
Purity >95% by SDS-PAGE.
Background
Introduction
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named for Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. The most common sources for Shiga toxin are the bacteria S. dysenteriae and the shigatoxigenic group of Escherichia coli (STEC), which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC).
Keywords
Shiga toxin; E. coli Stx2; stx2; Stx2; Stx-2; Shiga-like toxin 2; SLT-2; SLT-II
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