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ficlatuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-HGF Therapeutic Antibody TAB-749 1mg Please Inquiry
Product Detail
Cat
TAB-749
Product Overview
Recombinant humanized antibody expressed in CHO binding to human HGF. Ficlatuzumab is a humanized monoclonal antibody designed for the treatment of cancers.
Target
HGF
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
CAS
1174900-84-5
Predicted N terminal
QVQLVQPG
Molecular Weight
145.41 kDa
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Size
1mg
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Introduction
Ficlatuzumab is a humanized monoclonal antibody designed for the treatment of cancers.
Antigen Description
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. IL-22 is an α-helical cytokine. IL-22 binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1 subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells.
Function
catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;
Gene ID
3082
Synonyms
HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39 , DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen; scatter factor; SF; hepatopoeitin-A; hepatopoietin-A; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; F-TCF; DFNB39;
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