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Anti-Human ANGPTL3 Therapeutic Antibody

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ANGPTL3 Therapeutic Antibody TAB-H30 1mg Please Inquiry
Product Detail
Cat
TAB-H30
Product Overview
Recombinant human antibody to Human ANGPTL3. mAb targeting angiopoietin-like 3 (ANGPTL3)
Type
IgG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
Protein Construction
γ4 heavy chain (1-453) [human VH (IGHV3-43*02 (93%) – (IGHD) – IGHJ3*02) [8.8.19] (1-126) – IGHG4*01 H S108>P (234) (127-453)] (140-214')– disulfide withkappa light chain (1'-214') [human V-KAPPA (IGKV1-5*03 (99%) – IGKJ2*01) [6.3.9] (1'-107') – IGKC*01 (108'-214')] dimer (232-232'':235-235'') –bisdisulfide
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Background
Antigen Description
ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism. ANGPTL3 monoclonal antibody recognizes the fibrinogen-like domain (FLD) of human ANGPTL3. It detects a band of ~68 kDa and a cleaved band of ~35 kDa by WB. It does not cross-react with other ANGPTL family proteins.
Function
cell surface binding; enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity;
Gene ID
27329
Synonyms
ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; ANG-5; FHBL2;
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