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Vepalimomab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human AOC3 Therapeutic Antibody TAB-137 1mg Please Inquiry
Product Detail
Cat
TAB-137
Product Overview
Recombinant monoclonal antibody to AOC3. Vepalimomab is a mouse monoclonal antibody developed for the treatment of inflammations. It blocks the vascular adhesion protein 1.
Target
AOC3
Type
IgM
Immunogen
Purified vessels from human peripheral lymph nodes.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS
195158-85-1
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin M (mouse monoclonal 1B2 μ-chain anti-human vascular adhesion protein VAP-1), disulfide with mouse monoclonal 1B2light chain, dimer
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.
Function
aliphatic-amine oxidase activity; aminoacetone:oxygen oxidoreductase(deaminating) activity; calcium ion binding; cation channel activity; copper ion binding; copper ion binding; oxidoreductase activity; phenethylamine:oxygen oxidoreductase (deaminating) a
Gene ID
8639
Synonyms
AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1;
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