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Odulimomab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD11a Therapeutic Antibody TAB-108 1mg Please Inquiry
Product Detail
Cat
TAB-108
Product Overview
Recombinant monoclonal antibody to CD11a. Odulimomab is an investigational drug for the prevention of transplant rejection and for the treatment of various immunological diseases. It is a mouse monoclonal antibody directed against the alpha chain of the protein lymphocyte function-associated antigen 1 which is involved in immune reactions.
Target
CD11a
Type
IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS
159445-64-4
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1,anti-(human CD11 (antigen) a-chain) (mouse monoclonal 25.3 g1-chain), disulfide with mouse monoclonal 25.3 lightchain, dimer
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Size
1mg
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Function
cell adhesion molecule binding; protein heterodimerization activity; receptor activity;
Gene ID
3683
Synonyms
ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; integrin alpha-L; LFA 1; LFA-1A; LFA-1 alpha; integrin gene promoter; CD11 antigen-like family member A; lymphocyte function-associated antigen 1; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; LFA-1; LFA1A;
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