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ziralimumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD147/BSG Therapeutic Antibody TAB-883 1mg Please Inquiry
Product Detail
Cat
TAB-883
Product Overview
Recombinant human monoclonal antibody expressed in CHO binding to human CD147. Ziralimumab is a human monoclonal antibody which is used as an immunosuppressive drug.
Target
CD147
Type
IgM
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
Molecular Weight
Approximately 150 kDa
Purity
>95.0% as determined by analysis by RP-HPLC.
Size
1mg
Storage
At -20°C for one year.
Background
Introduction
Ziralimumab is a human monoclonal antibody which is used as an immunosuppressive drug.
Antigen Description
Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Function
lactate transmembrane transporter activity; mannose binding; sugar binding;
Gene ID
682
Synonyms
BSG; basigin (Ok blood group); basigin (OK blood group) , OK; basigin; CD147; EMMPRIN; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor; M6; OK; 5F7; TCSF;
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