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Afutuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD20 Therapeutic Antibody TAB-133 1mg Please Inquiry
Product Detail
Cat
TAB-133
Product Overview
Recombinant monoclonal antibody to CD20. Afutuzumab is a monoclonal antibody for the treatment of lymphoma. It acts as an immunomodulator.
Target
CD20
Type
IgG3 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS
949142-50-1
Specificity
Tested positive against native human antigen.
Protein Construction
immunoglobulin G1, anti-[Homo sapiens CD20], humanized monoclonal antibody, GA101; gamma1 heavy chain (1-448) [humanized VH (Homo sapiens FR/Mus musculus CDR, Homo sapiens IGHJ4*01) [8.8.12] (1-119) -Homo sapiens IGHG1*01 (120-448)], (222-219")-disulfide with kappa light chain (1"-219") [humanized V-KAPPA (Homo sapiens FR/Mus musculus CDR, Homo sapiens IGKJ4*01) [11.3.9] (1"-112") -Homo sapiens IGKC*01 (113"-219")]; (228-228"":231-231"")-bisdisulfide dimer
Predicted N terminal
H chain: QVQLVQS; L chain: DIVMTQS
Molecular Weight
146062
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
CD20 is B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells.
Function
epidermal growth factor receptor binding;
Gene ID
931
Synonyms
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1; S7; CVID5; LEU-16; MGC3969;
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