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Iratumumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD30 Therapeutic Antibody TAB-144 1mg Please Inquiry
Product Detail
Cat
TAB-144
Product Overview
Recombinant monoclonal antibody to CD30. Iratumumab is a human monoclonal antibody used in the treatment of oncological diseases such as relapsed refractory CD30-positive lymphoma including Hodgkin's disease.
Target
CD30
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS
640735-09-7
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti- (human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer
Molecular Weight
170000
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Function
binding; receptor activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;
Gene ID
943
Synonyms
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30, D1S166E; tumor necrosis factor receptor superfamily member 8; KI 1; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30; CD30; Ki-1; D1S166E;
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