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Priliximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD4 Therapeutic Antibody (Centara) TAB-164 1mg Please Inquiry
Product Detail
Cat
TAB-164
Product Overview
Recombinant monoclonal antibody to CD4. Priliximab (cMT 412) is a human-mouse chimeric anti-CD4 monoclonal antibody. It has been tested on patients with Crohn's disease and multiple sclerosis but has not yet received U.S. Food and Drug Administration licencing.
Target
CD4
Type
IgG1 - kappa
Immunogen
P815 mastocytoma ce11stransfected with human CD4 cDNA
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS
147191-91-1
Trade name
centara
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1,anti-(human CD4 (antigen)) (human-mouse monoclonal cm-T412 g1-chain), disulfide withhuman-mouse monoclonal cm-T412 k-chain, dimer
Purity
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Function
MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling re
Gene ID
920
Synonyms
CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
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