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Cedelizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD4 Therapeutic Antibody TAB-107 1mg Please Inquiry
Product Detail
Cat
TAB-107
Product Overview
Recombinant monoclonal antibody to CD4. Cedelizumab is a monoclonal antibody acting on the immune system. Possible indications include the prevention of organ transplant rejections and the treatment of autoimmune diseases.
Target
CD4
Type
IgG4 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
CAS
156586-90-2
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G4, anti-(human CD4 (antigen)) (human-mouse monoclonal OKTcdr4a complementary determining region-grafted gamma4-chain), disulfide with human-mouse monoclonal OKTcdr4a complementary determining region-grafted kappa-chain, dimer
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Function
MHC class II protein binding; coreceptor activity; enzyme binding; extracellular matrix structural constituent; glycoprotein binding; protein binding; protein homodimerization activity; protein kinase binding; receptor activity; transmembrane signaling re
Gene ID
920
Synonyms
CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
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