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Patritumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ERBB3 Therapeutic Antibody TAB-189 1mg Please Inquiry
Product Detail
Cat
TAB-189
Product Overview
Recombinant monoclonal antibody to ErbB3. Patritumab (INN) is a human monoclonal designed for the treatment of cancer. It acts as an immunomodulator.
Target
ERBB3
Type
IgG1 - kappa
Immunogen
HER3 ECD protein
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
CAS
1262787-83-6
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)], Homo sapiens monoclonalantibody; gamma1 heavy chain (1-447)-disulfide with kappa light chain (1"-220")-bisdisulfide dimer
Predicted N terminal
H chain: QVQLQQW; L chain: DIEMTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Binds and is activated by neuregulins and NTAK.
Function
ATP binding; growth factor binding; growth factor binding; nucleotide binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; protein homodimerization activity; protein tyrosine kinase activator activity; NOT pr
Gene ID
2065
Synonyms
ERBB3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); LCCS2, lethal congenital contracture syndrome 2; receptor tyrosine-protein kinase erbB-3; HER3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; MGC88033;
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