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Solitomab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human EpCAM Therapeutic Antibody TAB-889 1mg Please Inquiry
Product Detail
Cat
TAB-889
Product Overview
Recombinant humanized antibody expressed in CHO binding to human EpCAM. Solitomab is a mouse monoclonal antibody designed for the treatment of cancer. It binds to EpCAM.
Target
EpCAM
Type
(scFv - kappa - heavy) - (scFv - heavy - kappa)
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
CAS
1005198-65-1
Predicted N terminal
ELVMTQSP
Molecular Weight
Approximately 150 kDa
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Size
1mg
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Introduction
Solitomab is a mouse monoclonal antibody designed for the treatment of cancer. It binds to EpCAM.
Antigen Description
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Function
protein binding;
Gene ID
4072
Synonyms
EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2;
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