|Anti-Human HGF Therapeutic Antibody
- Product Overview
- Recombinant monoclonal antibody to HGF. Flanvotumab is a human monoclonal antibody designed for the treatment of melanoma.
- IgG1 - kappa
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Expression Host
- Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
- Tested positive against native human antigen.
- Protein Construction
- Immunoglobulin G1, anti-(human glycoprotein gp75) (human monoclonal IMC-20D7S heavy chain), disulfide with human monoclonal IMC-20D7S light chain, dimer
- Predicted N terminal
- H chain: QVQLVQS; L chain: EIVLTQS
- Molecular Weight
- >95.0% as determined by analysis by SDS-PAGE.
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
- Antigen Description
- HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
- catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;
- Gene ID
- HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39 , DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen; scatter factor; SF; hepatopoeitin-A; hepatopoietin-A; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; F-TCF; DFNB39;
- Download Datasheet:
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