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Flanvotumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human HGF Therapeutic Antibody TAB-130 1mg Please Inquiry
Product Detail
Cat
TAB-130
Product Overview
Recombinant monoclonal antibody to HGF. Flanvotumab is a human monoclonal antibody designed for the treatment of melanoma.
Target
HGF
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
CAS
1188277-05-5
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human glycoprotein gp75) (human monoclonal IMC-20D7S heavy chain), disulfide with human monoclonal IMC-20D7S light chain, dimer
Predicted N terminal
H chain: QVQLVQS; L chain: EIVLTQS
Molecular Weight
145543
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
Function
catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; NOT serine-type endopeptidase activity;
Gene ID
3082
Synonyms
HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39 , DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen; scatter factor; SF; hepatopoeitin-A; hepatopoietin-A; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; F-TCF; DFNB39;
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