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Rontalizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IFN alpha Therapeutic Antibody TAB-074 1mg Please Inquiry
Product Detail
Cat
TAB-074
Product Overview
Recombinant monoclonal antibody to IFN alpha. Rontalizumab is a humanized monoclonal antibody. for treatment of systemic lupus erythematosus.
Target
IFN alpha
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
CAS
948570-30-7
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1-kappa, anti-[Homo sapiens interferon alpha (IFN-alpha)], humanized monoclonal antibody; gamma1 heavy chain [humanized VH (Homo sapiens IGHV3-74*01(76.30%) -(IGHD)-IGHJ4*01) [8.8.10] (1-117) -Homo sapiens IGHG1*03, CH1 R120>K (118-447)], (220-218")-disulfide with kappa light chain (1"-218") [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (83.80%) -IGKJ1*01) [10.3.9] (1"-111") -Homo sapiens IGKC*01 (112"-218")]; (226-226":229-229")-bisdisulfide dimer
Predicted N terminal
H Chain: EVQLVES; L Chain: DIQMTQS
Molecular Weight
145900
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Gene ID
3439
Synonyms
IFNA1; interferon, alpha 1; interferon alpha-1/13; IFL; IFN; IFN ALPHA; IFN alpha 1b; IFN alphaD; IFNA13; IFNA@; interferon alpha 1b; leIF D; IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; interferon alpha-D; IFN-ALPHA; IFN-alphaD; MGC138207; MGC138505; MGC138507;
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