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anrukinzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL13 Therapeutic Antibody TAB-H05 1mg Please Inquiry
Product Detail
Cat
TAB-H05
Product Overview
Recombinant Humanized (from mouse) antibody to Human IL13. Anrukinzumab (IMA-638) is a humanized monoclonal antibody designed for the treatment of asthma.
Type
IgG1
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, IHC and most other immunological methods.
CAS
910649-32-0
Specificity
IL13 (interleukin 13, IL-13) [Homo sapiens]
Protein Construction
gamma1 heavy chain [humanized VH (Homo sapiens FR/Mus musculus CDR) [8.7.12] -Homo sapiens IGHG1*03, 97R>K (CH1 120), 117L>A (CH2 1.3),120G>A (CH2 1] (221-218')-disulfide withkappa light chain [humanized V-KAPPA (Homo sapiens FR/Mus musculus CDR) [10.3.9] -Homo sapiens IGKC*01]; (227-227'':230-230'')-bisdisulfidedimer
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Background
Antigen Description
Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located on chromosome 5q31 with a length of 1.4kb. IL-13 and IL-4 exhibit a 30% of sequence similarity and have a similar structure.
Function
cytokine activity; interleukin-13 receptor binding; protein binding;
Gene ID
3596
Synonyms
IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;
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