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Secukinumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL17A Therapeutic Antibody TAB-069 1mg Please Inquiry
Product Detail
Cat
TAB-069
Product Overview
Recombinant monoclonal antibody to IL17A. Secukinumab is a human monoclonal antibody designed for the treatments of uveitis, rheumatoid arthritis, and psoriasis. It targets member A from the cytokine family of interleukin 17.
Target
IL17A
Type
IgG1 - kappa
Immunogen
HuIL-17 coupled 10 KLH mixed 1:1 with huIL-17 in Gerbu adjuvant.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
CAS
875356-43-7
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human interleukin-17A (IL-17, cytotoxic T-lymphocyte-associated antigen 8)); human monoclonal AIN457 γ1 heavy chain (230-215")-disulfide with human monoclonal AIN457 kappa light chain dimer
Predicted N terminal
H Chain: EVQLVES; L Chain: EIVLTQS
Molecular Weight
147940
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
At -20°C for one year.
Background
Antigen Description
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.
Function
cytokine activity;
Gene ID
3605
Synonyms
IL17A; interleukin 17A; CTLA8, IL17, interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); interleukin-17A; cytotoxic T lymphocyte associated protein 8; IL 17; IL 17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); IL17; CTLA8; IL-17; IL-17A;
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