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Pascolizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL4 Therapeutic Antibody TAB-221 1mg Please Inquiry
Product Detail
Cat
TAB-221
Product Overview
Recombinant monoclonal antibody to IL4. Pascolizumab is a humanized monoclonal antibody for the treatment of asthma.
Target
IL4
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.
CAS
331243-22-2
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human interleukin 4) (human-mouse monoclonal SB-240683 g1-chain), disulfide with human-mouse monoclonal SB-240683 k-chain, dimer
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Function
cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding;
Gene ID
3565
Synonyms
IL4; interleukin 4; interleukin-4; B cell growth factor 1; B_cell stimulatory factor 1; BCGF 1; BCGF1; BSF1; IL 4; lymphocyte stimulatory factor 1; MGC79402; binetrakin; pitrakinra; IL-4; BSF-1; BCGF-1;
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