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Vatelizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ITGA2 Therapeutic Antibody TAB-251 1mg Please Inquiry
Product Detail
Cat
TAB-251
Product Overview
Recombinant monoclonal antibody to ITGA2. Vatelizumab is an immunomodulator. It binds to integrin alpha 2
Target
ITGA2
Type
IgG4 - kappa
Immunogen
Whole human keratinocytes.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
CAS
1238217-55-4
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G4-kappa, anti-[Homo sapiens ITGA2 (integrin alpha 2, CD49b, GPIa, subunit of the alpha2beta1 integrin (VLA-2, collagen receptor))], humanized monoclonal antibody
Predicted N terminal
H chain: QVQLQES; L chain: DIVMTQS
Purity
>95.0% as determined by analysis by RP-HPLC.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Function
collagen binding; protein binding; receptor activity;
Gene ID
3673
Synonyms
ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49B; integrin alpha-2; CD49b; integrin alpha 2; collagen receptor; VLA-2 subunit alpha; platelet antigen Br; platelet glycoprotein Ia; platelet glycoprotein GPIa; CD49 antigen-like family member B; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; BR; GPIa; VLA-2; VLAA2; BDPLT9;
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