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Anrukinzumab (= IMA-638)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human ITGA3 Therapeutic Antibody TAB-252 1mg Please Inquiry
Product Detail
Cat
TAB-252
Product Overview
Recombinant monoclonal antibody to ITGA3. Anrukinzumab (IMA-638) is a humanized monoclonal antibody designed for the treatment of asthma.
Target
IL-13
Type
Humanized (from mouse) IgG1 Kappa
Immunogen
Recombinant full length protein (Human).
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
CAS
910649-32-0
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human CD40 (antigen)) (human-mouse monoclonal SGN-40 γ1-chain), disulfide with human-mouse monoclonal SGN-40 Kappa-chain, dimer
Predicted N terminal
H chain: EVQLVES; L chain: DIQMTQS
Molecular Weight
145400
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
Function
cytokine activity; interleukin-13 receptor binding; protein binding;
Gene ID
3596
Synonyms
IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;
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