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Anti-INS Protein A Scaffold, HRP-Conjugated

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Insulin Protein A scaffold, HRP-Conjugated AFB-36LY 1mg Please Inquiry
Product Detail
Cat
AFB-36LY
Product Overview
The Anti-Insulin Protein A Scaffold molecule was selected against recombinant human insulin (chain A and B). The molecule is conjugated with maleimide activated horseradish peroxidase (HRP) at the unique C-terminal cysteine. The HRP-Conjugated Anti-Insulin Protein A Scaffold molecule is excellent for immunohistochemical staining of frozen and paraffin embedded tissue sections.
Species Reactivity
human
Expression Host
E. coli
Applications
Immunohistochemical staining of frozen and paraffin embedded tissue sections.
Specificity
Anti-Insulin Protein A scaffold molecule binds to human, mouse and rat insulin.
Storage
At -20°C. Avoid freezing. There is no decrease in performance of the HRP-Conjugated Protein A Scaffold molecule after storage for 2 weeks in room temperature.
Background
Antigen Description
The 5.7 kDa polypeptide hormone insulin is structured as two polypeptide chains, the 21 amino acid A chain and the 30 amino acid B chain, linked by two disulphide bonds. Insulin is synthesized in the beta cells of the islets of Langerhans in the pancreas as a prohormone; proinsulin that is later transformed by proteolytic action into the active hormone. Insulin excerts multiple actions throughout the body to regulate the energy metabolism. Its anabolics action includes build-up and storage of glycogen and fat.
Function
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Gene ID
3630
Synonyms
INS; insulin; ILPR; IRDN; IDDM2; MODY10; IN; proinsulin; Insulin B chain; Insulin A chain; OTTHUMP00000011161; OTTHUMP00000011162; OTTHUMP00000196036; OTTHUMP00000196038; OTTHUMP00000217519
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