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Simtuzumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human LOXL2 Therapeutic Antibody TAB-890 1mg Please Inquiry
Product Detail
Cat
TAB-890
Product Overview
Recombinant humanized antibody expressed in CHO binding to human LOXL2. Simtuzumab is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator.
Target
LOXL2
Type
IgG4 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS
1318075-13-6
Predicted N terminal
QVQLVQSG
Molecular Weight
147.5 kDa
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Introduction
Simtuzumab is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator.
Antigen Description
Expressed in many tissues. Highest expression in reproductive tissues, placenta, uterus and prostate.
Function
copper ion binding; electron carrier activity; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; scavenger receptor activity;
Gene ID
4017
Synonyms
LOXL2; lysyl oxidase-like 2; lysyl oxidase homolog 2; WS9 14; lysyl oxidase related 2; lysyl oxidase-like protein 2; lysyl oxidase-related protein 2; lysyl oxidase-related protein WS9-14; LOR2; WS9-14;
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