Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Carlumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human MCP-1 Therapeutic Antibody TAB-117 1mg Please Inquiry
Product Detail
Cat
TAB-117
Product Overview
Recombinant monoclonal antibody to MCP-1. Crenezumab is a humanized monoclonal antibody against human 1-40 and 1-42 Beta amyloid, which is being investigated as a treatment of Alzheimer's disease.
Target
MCP-1
Type
IgG1 - kappa
Immunogen
Recombinant hMCAF/MCP-1 (human Macrophage/Monocyte chemotactic protein-1)
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
CAS
1174395-19-7
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobuline G2-kappa, anti-[Homo sapiens IL17RA (récepteur A de l"interleukine 17, CD217)], Homo sapiens anticorps monoclonal
Predicted N terminal
H chain: QVQLVQS; L chain: EIVMTQS
Molecular Weight
144880
Purity
>95.0% as determined by analysis by RP-HPLC.
Size
1mg
Storage
At -20°C for one year.
Background
Antigen Description
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Function
CCR2 chemokine receptor binding; CCR2 chemokine receptor binding; G-protein coupled receptor binding; chemokine activity; heparin binding; protein kinase activity; receptor binding;
Gene ID
6347
Synonyms
CCL2; chemokine (C-C motif) ligand 2; SCYA2, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); C-C motif chemokine 2; GDCF 2; HC11; MCAF; MCP 1; MCP1; MGC9434; monocyte chemoattractant protein 1; monocyte chemotactic and activating factor; monocyte chemotactic protein 1; homologous to mouse Sig je; monocyte secretory protein JE; small inducible cytokine subfamily A (Cys Cys); member 2; SMC CF; small-inducible cytokine A2; monocyte chemoattractant protein-1; small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30;
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-048-3343


© 2007 - 2017 Creative-Biolabs All Rights Reserved