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yttrium (90 Y) clivatuzumab tetraxetan

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human MUC1 Therapeutic Antibody (hPAM4-Cide) TAB-H77 1mg Please Inquiry
Product Detail
Cat
TAB-H77
Product Overview
Recombinant Humanized antibody to Human MUC1. Yttrium (90Y) clivatuzumab tetraxetan (trade name hPAM4-Cide) is a humanized monoclonal antibody designed for the treatment of pancreatic cancer.[1] The antibody itself, clivatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90,[2] a radioisotope which destroys the tumour cells.
Type
IgG1 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS
943976-23-6
Trade name
hpam4-cide
Specificity
MUC1 (mucin 1, polymorphic epithelial mucin, PEM, episialin, CD227) [Homo sapiens]
Purity
Purity >95% by SDS-PAGE.
Background
Antigen Description
Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs
Function
RNA polymerase II core promoter proximal region sequence-specific DNA binding; p53 binding; protein binding; transcription cofactor activity;
Gene ID
4582
Synonyms
MUC1; mucin 1, cell surface associated; mucin 1, transmembrane , PUM; mucin-1; CD227; PEM; episialin; DF3 antigen; H23 antigen; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; EMA; PUM; KL-6; MAM6; PEMT; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC;
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