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Amatuximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Mesothelin Therapeutic Antibody TAB-201 1mg Please Inquiry
Product Detail
Cat
TAB-201
Product Overview
Recombinant monoclonal antibody to Mesothelin. Amatuximab is a chimeric monoclonal antibody designed for the treatment of cancer.
Target
Mesothelin
Type
IgG1 - kappa
Immunogen
Spleen lymphocytes from mice fused with OVCAR-3, an ovarian tumorcell line derived from poorly differentiated adenocarcinoma of the ovary.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS
931402-35-6
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(mesothelin) (human-mouse monoclonal MORAb-009 heavy chain), disulfide with human-mouse monoclonal MORAb-009 kappa-chain, dimer
Predicted N terminal
H chain: QVQLQQS; L chain: DIELTQS
Molecular Weight
144329
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Gene ID
10232
Synonyms
MSLN; mesothelin; CAK1; MPF; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; SMRP;
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