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Stamulumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Myostatin/GDF8 Therapeutic Antibody TAB-888 1mg Please Inquiry
Product Detail
Cat
TAB-888
Product Overview
Recombinant monoclonal antibody expressed in CHO binding to human Myostatin. Stamulumab is an experimental myostatin inhibiting drug for the treatment of muscular dystrophy (MD). Myostatin is a protein that inhibits the growth of muscle tissue, stamulumab is a recombinant human antibody designed to bind to and inhibit the activity of myostatin. Stamulumab is a G1 immunoglobulin antibody which binds to myostatin and prevents it from binding to its target site, thus inhibiting the growth-limiting action of myostatin on muscle tissue.
Target
Myostatin
Type
IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS
705287-60-1
Predicted N terminal
MQKLQLCV
Molecular Weight
137.5 kDa
Purity
>95.0% as determined by analysis by RP-HPLC.
Size
1mg
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Introduction
Stamulumab is an experimental myostatin inhibiting drug for the treatment of muscular dystrophy (MD). Myostatin is a protein that inhibits the growth of muscle tissue, stamulumab is a recombinant human antibody designed to bind to and inhibit the activity of myostatin. Stamulumab is a G1 immunoglobulin antibody which binds to myostatin and prevents it from binding to its target site, thus inhibiting the growth-limiting action of myostatin on muscle tissue.
Antigen Description
Acts specifically as a negative regulator of skeletal muscle growth.
Function
cytokine activity; growth factor activity; receptor binding; contributes_to receptor binding;
Gene ID
2660
Synonyms
MSTN; myostatin; GDF8, growth differentiation factor 8; growth/differentiation factor 8; GDF-8; growth differentiation factor 8; GDF8; MSLHP;
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