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Pidilizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human PD-1/PDCD1/CD279 Therapeutic Antibody TAB-900 1mg Please Inquiry
Product Detail
Cat
TAB-900
Product Overview
Recombinant humanized (from mouse) antibody expressed in CHO binding to human PD-1. Pidilizumab is a monoclonal antibody designed for the treatment of cancer and infectious diseases.
Target
PD-1
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS
1310680-64-8
Molecular Weight
147.43 kDa
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Introduction
Pidilizumab is a monoclonal antibody designed for the treatment of cancer and infectious diseases.
Antigen Description
Possible cell death inducer, in association with other factors. Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Function
protein binding; protein tyrosine phosphatase activity; signal transducer activity;
Gene ID
5133
Synonyms
PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l;
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