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Anti-Human PDCD1 Therapeutic Antibody

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human PDCD1 Therapeutic Antibody TAB-H55 1mg Please Inquiry
Product Detail
Cat
TAB-H55
Product Overview
Recombinant Humanized (from mouse) antibody to Human PDCD1. It is a drug that targets the programmed cell death 1 (PD-1) receptor. The drug is intended for use in treating metastatic melanoma.
Type
IgG4 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, WB and most other immunological methods.
CAS
1374853-91-4
Specificity
PDCD1(programmed cell death 1, PD-1, PD1, CD279) [Homo sapiens]
Protein Construction
humanized mouse monoclonal [228- L- proline(H10- S>P)]γ4 heavy chain (134-218') – disulfide with humanized mouse monoclonal κ light chain dimer (226-226':229-229')
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Background
Antigen Description
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells. PD-1 binds two ligands, PD-L1 and PD-L2.
Function
protein binding; protein tyrosine phosphatase activity; signal transducer activity;
Gene ID
5133
Synonyms
PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l;
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