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enfortumab vedotin

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human PVRL4 Therapeutic Antibody TAB-H25 1mg Please Inquiry
Product Detail
Cat
TAB-H25
Product Overview
Recombinant human antibody to Human PVRL4
Type
IgG1 - kappa
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, Neut, IF, IP, FC, FuncS and most other immunological methods.
CAS
1346452-25-2
Specificity
PVRL4 (poliovirus receptor-related 4, nectin-4, nectin 4, PPR4, LNIR) [Homo sapiens]
Protein Construction
gamma1 heavy chain (1-447) [Homo sapiens VH (IGHV3-48*02 (98.00%) – (IGHD)-IGHJ6*01) [8.8.10] (1-117) – IGHG1*03 (CH1 (118-215), hinge(216-230), CH2 (231-340), CH3 (341-445), CHS (446-447)) (118-447)], (220-214') – disulfide withkappa light chain (1'-214') [Homo sapiens V-KAPPA (IGKV1-12*01 (96.80%) – IGKJ4*01) [6.3.9] (1'-107') – IGKC*01 (108'-214')]; dimer (226-226'':229-229'') – bisdisulfide;
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Background
Antigen Description
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
Function
protein binding;
Gene ID
81607
Synonyms
PVRL4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; LNIR; nectin 4; PRR4; Ig superfamily receptor LNIR; Nectin 4; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; PRR4; pvrl4; PVRL4_HUMAN; OTTHUMP00000029698; Ig superfamily receptor LNIR; EDSS1; nectin-4;
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