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Bavituximab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Phosphatidylserine Therapeutic Antibody TAB-175 1mg Please Inquiry
Product Detail
Cat
TAB-175
Product Overview
Recombinant monoclonal antibody to phosphatidylserine. Bavituximab is a chimeric monoclonal antibody designed for the treatment of cancers and viral infections.
Target
phosphatidylserine
Type
IgG1 - kappa
Immunogen
Liposomes containing 70% phosphatidylserine and 30% phosphatidylglycerol.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS
648904-28-3
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1,anti-(phosphatidylserine) (human-mouse monoclonal ch3G4 heavy chain), disulfidewith human-mouse monoclonal ch3G4 k-chain, dimer
Predicted N terminal
H chain: EVQLQQS; L chain: DIQMTQS
Molecular Weight
145300
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Introduction
Chimeric monoclonal antibody designed for the treatment of cancers and viral infections.
Antigen Description
Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid component, usually kept on the inner-leaflet (the cytosolic side) of cell membranes by an enzyme called flippase. When a cell undergoes apoptosis, phosphatidylserine is no longer restricted to the cytosolic part of the membrane, but becomes exposed on the surface of the cell.
Keywords
Phosphatidylserine; PS; Ptd-L-Ser
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