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Pateclizumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human TNF beta therapeutic Antibody TAB-071 1mg Please Inquiry
Product Detail
Cat
TAB-071
Product Overview
Recombinant monoclonal antibody to TNF beta. Pateclizumab is an immunomodulator. It binds to lymphotoxin alpha.
Target
TNF beta
Type
IgG1 - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS
1202526-59-7
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G1, anti-(human lymphotoxin alpha) (human-mouse monoclonal MLTA3698A heavy chain), disulfide with human-mouse monoclonal MLTA3698A light chain, dimer
Predicted N terminal
H Chain: EVQLVES; L Chain: DIQMTQS
Molecular Weight
144714
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Antigen Description
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Function
cytokine activity; receptor binding; tumor necrosis factor receptor binding;
Gene ID
4049
Synonyms
LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;
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