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mapatumumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human TNFRSF10A Therapeutic Antibody TAB-H48 1mg Please Inquiry
Product Detail
Cat
TAB-H48
Product Overview
Recombinant human antibody to Human TNFRSF10A. Mapatumumab (HGS-ETR1) is an experimental human monoclonal antibody for the treatment of cancer.
Type
IgG1
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, IHC and most other immunological methods.
CAS
658052-09-6
Specificity
TNFRSF10A(tumor necrosis factor receptor (TNFR) superfamily member 10A, death receptor 4, DR4, TNF-related apoptosis-inducing ligand receptor 1, TRAILR1, TRAIL-R1, TR-1, CD261) agonistic antibody [Homo sapiens]
Protein Construction
immunoglobulin G1, anti-(human cytokine receptor DR4 (death receptor 4))(human monoclonal TRM-1 heavy chain), disulfide with humanmonoclonal TRM-1 λ-chain, dimer
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Background
Antigen Description
Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002
Function
TRAIL binding; death receptor activity; protein binding; receptor activity; transcription factor binding;
Gene ID
8797
Synonyms
TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; tumor necrosis factor receptor superfamily member 10A; Apo2; CD261; DR4; TRAILR 1; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2; APO2; TRAILR1; TRAILR-1; MGC9365;
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