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Tenatumomab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Tenascin C/TNC Therapeutic Antibody TAB-877 1mg Please Inquiry
Product Detail
Cat
TAB-877
Product Overview
Recombinant humanized (from mouse) antibody expressed in CHO binding to human Tenascin C/TNC. Tenatumomab is a monoclonal antibody designed for the treatment of cancer.
Target
Tenascin C/TNC
Type
IgG2b
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
Predicted N terminal
EIQLQQSG
Molecular Weight
Approximately 150 kDa
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Introduction
Tenatumomab is a monoclonal antibody designed for the treatment of cancer.
Antigen Description
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
Function
binding; receptor binding; syndecan binding;
Gene ID
3371
Synonyms
TNC; tenascin C; hexabrachion (tenascin C, cytotactin) , HXB; tenascin; hexabrachion (tenascin); MGC167029; TN; GP 150-225; cytotactin; neuronectin; myotendinous antigen; tenascin-C isoform 14/AD1/16; glioma-associated-extracellular matrix antigen; GP; JI; HXB; GMEM; TN-C; 150-225;
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