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Alacizumab pegol

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human VEGF Receptor 2 Therapeutic Antibody, F(ab')2 fragment TAB-202 1mg Please Inquiry
Product Detail
Cat
TAB-202
Product Overview
Recombinant antibody fragment Fab to VEGF Receptor 2. Alacizumab pegol is an antineoplastic agent. Chemically, it is a pegylated F(ab')2 fragment of a monoclonal antibody.
Target
VEGF Receptor 2
Type
di - Fab'
Immunogen
Recombinant human soluble extracellular KDR (110 kDa) native protein.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
CAS
934216-54-3
Specificity
Tested positive against native human antigen.
Predicted N terminal
H chain: EVQLVES; L chain: DIQMTQS
Purity
Purity >95% by SDS-PAGE.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.
Function
ATP binding; Hsp90 protein binding; growth factor binding; integrin binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyro
Gene ID
3791
Synonyms
KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;
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