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Pritumumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Vimentin Therapeutic Antibody TAB-214 1mg Please Inquiry
Product Detail
Cat
TAB-214
Product Overview
Recombinant monoclonal antibody to Vimentin. Pritumumab is a human monoclonal antibody used in the treatment of brain cancer.
Target
Vimentin
Type
IgG1
Immunogen
synthetic acetylated peptide of Human Vimentin.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
CAS
499212-74-7
Specificity
Tested positive against native human antigen.
Protein Construction
Immunoglobulin G, anti-(human vimentin) (human monoclonal CLN G11 g1-chain), disulfide with human monoclonal CLN G11 k-chain, dimer
Molecular Weight
150000
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
Function
identical protein binding; protein C-terminus binding; protein binding; structural constituent of cytoskeleton;
Gene ID
7431
Synonyms
VIM; vimentin; FLJ36605;
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