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Radretumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human fibronectin extra domain-B Therapeutic Antibody TAB-193 1mg Please Inquiry
Product Detail
Cat
TAB-193
Product Overview
Recombinant monoclonal antibody to fibronectin extra domain-B. Radretumab is an antineoplastic. It binds to fibronectin extra domain-B.
Target
fibronectin extra domain-B
Type
[(scFv - heavy - kappa) - IGHE - CH4]2
Immunogen
A region in the ED-A domain of human cellular fibronectin.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
CAS
1253180-81-2
Specificity
Tested positive against native human antigen.
Purity
>95.0% as determined by analysis by SDS-PAGE.
Size
1mg
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans.
Function
collagen binding; extracellular matrix structural constituent; heparin binding; protein binding;
Gene ID
2335
Synonyms
FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;
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