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Brodalumab (CAT#: TAB-134)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL17RA Recombinant Antibody TAB-134 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IL17A. Crenezumab is a humanized monoclonal antibody against human 1-40 and 1-42 Beta amyloid, which is being investigated as a treatment of Alzheimer's disease.
  • Target
  • IL17RA
  • Type
  • IgG2 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • CAS
  • 1174395-19-7
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G2, anti-(human interleukin-17 receptor A (IL-17RA, CDw217, CD217)); human monoclonal AMG827 γ2 heavy chain (130-214")-disulfide with human monoclonal AMG827 kappa light chain dimer (218-218"":219-219"":222-222"":225-225"")- tetrakisdisulfide
  • Molecular Weight
  • 144060
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Interleukin 17 Receptor Alpha is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
  • Function
  • interleukin-17 receptor activity; receptor activity;
  • Synonyms
  • IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262;

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