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Rafivirumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-Rabies virus Therapeutic Antibody TAB-101 1mg Please Inquiry
Product Detail
Cat
TAB-101
Product Overview
Recombinant monoclonal antibody to Rabies virus glycoprotein. Rafivirumab is a monoclonal antibody for the prophylaxis of rabies.
Target
Rabies virus
Type
IgG1 - lambda
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Rabies virus
Expression Host
CHO
Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
CAS
944548-37-2
Specificity
Tested positive against native Rabies virus antigen
Protein Construction
ImmunoglobulinG1, anti-(rabies virus glycoprotein) (human monoclonal CR57 heavy chain),disulfide with human monoclonal CR57 k-chain, dimer
Predicted N terminal
H chain: QVQLVQS; L chain: QSALTQP
Molecular Weight
145800
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Size
1mg
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Introduction
Recombinant monoclonal antibody (from direct b cell isolation antibody) for the prophylaxis of rabies.
Antigen Description
Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
Keywords
rabies virus; rabies virus glycoprotein
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