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efungumab

DESCRIPTION CATALOG # SIZE PRICE
Anti-fungal Hsp90 Therapeutic Antibody (MYCOGRAB) TAB-704 1mg Please Inquiry
Product Detail
Cat
TAB-704
Product Overview
Recombinant human monoclonal antibody scFv fragment expressed in E. Coli binding to heat shock protein 90 homolog [Candida albicans]. Efungumab is a drug intended to treat invasive Candida infection in combination with amphotericin B.
Target
heat shock protein 90 homolog [Candida albicans]
Type
scFv - heavy - kappa
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
fungal
Expression Host
E. Coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, WB and most other immunological methods.
CAS
762260-74-2
Trade name
mycograb
Predicted N terminal
MAEVQLVE
Molecular Weight
27.2 kDa
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Size
1mg
Storage
Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Background
Introduction
Efungumab is a single-chain variable fragment of a human monoclonal antibody, intended to treat invasive Candida infection in combination with amphotericin B.
Antigen Description
C. albicans is commensal and a constituent of the normal gut flora comprising microorganisms that live in the human mouth and gastrointestinal tract. C. albicans lives in 80% of the human population without causing harmful effects, although overgrowth of the fungus results in candidiasis (candidosis).
Keywords
fungal Hsp90
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