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MemProArt™ Anti-Transporter Antibody Production

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The team of Creative Biolabs has excellent experts good at screening and expression of antibody targeting transporters. Creative Biolabs is able to meet all needs of customers from all over the world.

It has been revealed that many types of drugs interact with transporters within an organism. Transporters absorb or excrete materials, including nutrients anddrugs, across the cell membrane. Thus, transporter-conscious drug design is an excellent method of delivering drugs to pharmaceutical target organs and provides advantages in absorption, distribution, excretion, and toxicity of drugs due to transport systems. Transporter-consciously designed drugs can not only effectively elicit activity but also control adverse side effects caused by off-targets and drug-drug interactions and, consequently, may show good performance in clinical trials.

With rich experiences in membrane proteins and antibodies, Creative Biolabs develops MemProArtTM platform to guarantee service from many aspects about antibody targeting transporter, including screening and expression of antibody but not limited. The main expression systems are Cell-based Expression system, Cell-free Expression system and Virus-like Particles (VLPs) and Lipoparticles system.

Cell-based Expression
Cell-free Expression
Virus-like Particles (VLPs) and Lipoparticles

Phage Display Library Screening and hybridoma technique are two main methods for screening of antibody targeting transporter, MemProArt™ platform also offer service about antibody screening.

Phage Display Library Screening
Mouse/Rat Hybridoma Production

General strategy for phage panning

Creative Biolabs provides custom anti-membrane proteins antibody production services including but not limited to:

Anti-GPCR antibody
Anti-Ion channels antibody
Anti-Transporters antibody

Chan, C.E.Z., Lim, A.P.C., MacAry, P.A., and Hanson, B.J. (2014). The role of phage display in therapeutic antibody discovery. Int Immunol 26, 649-657.


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