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Anti-B. anthracis PA Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-B. anthracis PA Antibody Fab Fragment MOM-18224-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18224-F(E)
Product Overview
Recombinant Human Antibody Fab Fragment binds selectively to Bacillus anthracis, expressed in Chinese Hamster Ovary cells(CHO)
Target
Bacillus anthracis
Type
Fab Fragment based on Human IgG1 - lambda
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
B. anthracis
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Introduction
This is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax.
Antigen Description
Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments.
Keywords
anthrax PA; Anthrax Protective Antigen; Anthrax toxins translocating protein; Bacillus anthracis Protective Antigen; PA 83; PA; PA83; Pag; PagA; Protective antigen
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