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Anti-B. anthracis PA Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-B. anthracis PA Antibody Fab Fragment MOM-18224-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18224-F(P)
Product Overview
Recombinant Human Antibody Fab Fragment specifically binds to Bacillus anthracis, expressed in E. coli
Target
Bacillus anthracis
Type
Fab Fragment based on Human IgG1 - lambda
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
B. anthracis
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Introduction
This is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax.
Antigen Description
Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments.
Keywords
anthrax PA; Anthrax Protective Antigen; Anthrax toxins translocating protein; Bacillus anthracis Protective Antigen; PA 83; PA; PA83; Pag; PagA; Protective antigen
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