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Anti-CCR4 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CCR4 Antibody Fab Fragment MOM-18187-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18187-F(P)
Product Overview
Recombinant Humanized (from mouse) Antibody Fab Fragment binds selectively to Human CCR4, expressed in E. coli
Target
CCR4
Type
Fab Fragment based on Humanized (from mouse) IgG1 - kappa
Immunogen
KLH conjugate CCR4 partial peptide
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIVMTQS
Purity
Purity >95% by SDS-PAGE.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; receptor activity; signal transducer activity;
Gene ID
1233
Synonyms
CCR4; chemokine (C-C motif) receptor 4; C-C chemokine receptor type 4; CC CKR 4; CD194; ChemR13; CKR4; CMKBR4; k5 5; CCR-4; C-C CKR-4; chemokine (C-C) receptor 4; K5-5; CC-CKR-4; HGCN:14099; MGC88293;
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