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Anti-CCR4 Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CCR4 Antibody scFv Fragment MOM-18187-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18187-S(P)
Product Overview
Recombinant Humanized (from mouse) Antibody scFv Fragment specifically binds to Human CCR4, expressed in E. coli
Target
CCR4
Type
scFv Fragment from Humanized (from mouse) IgG1 - kappa
Immunogen
KLH conjugate CCR4 partial peptide
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; receptor activity; signal transducer activity;
Gene ID
1233
Synonyms
CCR4; chemokine (C-C motif) receptor 4; C-C chemokine receptor type 4; CC CKR 4; CD194; ChemR13; CKR4; CMKBR4; k5 5; CCR-4; C-C CKR-4; chemokine (C-C) receptor 4; K5-5; CC-CKR-4; HGCN:14099; MGC88293;
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