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Recombinant Anti-Human CD20 monoclonal antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human CD20 monoclonal antibody CRP08139 1mg Please Inquiry
Product Detail
Cat
CRP08139
Product Overview
Recombinant Anti-Human CD20 monoclonal antibody produced in CHO has a molecular mass of 80.0 kDa.
Specificity
Fully biologically active when compared to standard determined by the apoptosis assay of Raji cell in vitro.
Endotoxin
Less than 1EU/μg of rAnti-CD20 MAb as determined by LAL method.
Purity
>95% by SDS-PAGE and HPLC analyses.
Storage
This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Background
Antigen Description
CD20 is a non-glycosylated phosphoprotein expressed on the surface of all mature B-cells.Membrane-spanning 4-domains, subfamily A, member 1, also known as MS4A1, is a human gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Function
receptor activity
Gene ID
931
Synonyms
B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; membrane-spanning 4-domains, subfamily A, member 1; CD20_HUMAN; Membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 2;B-lymphocyte surface antigen B1;Leu-16;Bp35;CD20 antigen; B-lymphocyte antigen CD20;B-lymphocyte cell-surface antigen B1;CD20 RECEPTOR;CD20 antigen.
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